Scientific and research activity
collaboration
Preclinical drug testing and development projects of the company are carried out at globally recognized research institutions based in Russia and abroad
collaboration
The locations cover a total of 18 countries, including major EU, US and Asian Universities, Institutes and CROs
activity
Over three years, 86 studies have been conducted
research methods
Using most recent pharmacology techniques which meet the national and global standards is ensured by collaboration with accredited pre-clinical research centers located in Russia and worldwide
and Research
Our R&D activity includes in-depth mechanism of action studies on the company’s products, as well as drug discovery and target identification projects
laboratory facilities
Our R&D laboratory is working to design novel QC systems and performs innovative basic research into drug development with the use of certified equipment and advanced methods, such as spectral assays, cellular techniques and immunosensors.
control
The R&D biotechnology projects we carry out in collaboration with Russian and foreign experts consistently contribute to the improvement of existing methods and development of new experimental techniques for use in research, production and quality control of the company’s products
collaboration
Our biotechnology work involves institutions in 10 countries, including largest EU and Asian Institutes and CROs
activity
Over 3 years, 35 studies have been conducted:
in Russia: 26 and abroad: 9
journals
The results of our research projects are available as monographs and articles in Russian and foreign scientific publications, and are regularly announced at international congresses and conferences held throughout Russia and abroad.
-
Don E., Farafonova O., Pokhil S., Barykina D., Nikiforova M., Shulga D., Borshcheva A.,
Tarasov S., Ermolaeva T., Epstein O. (2016). Use of Piezoelectric Immunosensors for
Detection of Interferon-Gamma Interaction with Specific Antibodies in the Presence of
Released-Active Forms of Antibodies to Interferon-Gamma. Sensors, 16(1), 96. doi:
10.3390/s16010096.
https://www.ncbi.nlm.nih.gov/pubmed/26791304
http://www.mdpi.com/1424-8220/16/1/96 -
Gavrilova E.S., Bobrovnik S.A., Sherriff G., Myslivets A.A., Tarasov S.A., Epstein O.I.
(2014). Novel approach to activity evaluation for release-active forms of
anti-interferon-gamma antibodies based on enzyme-linked immunoassay. PloS one, 9(5), e97017.
doi: 10.1371/journal.pone.0097017.
https://www.ncbi.nlm.nih.gov/pubmed/24816648
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097017 -
Pschenitza M., Gavrilova Е.S., Tarasov S.А., Knopp D., Niessner R., Epstein О.I.
(2014). Application of a heterogeneous immunoassay for the quality control testing
of release-active forms of diclofenac. International immunopharmacology, 21(1), 225-230.
https://www.ncbi.nlm.nih.gov/pubmed/24836753 -
Sakat S.S., Mani K., Demidchenko Y.O., Gorbunov E.A., Tarasov S.A., Mathur A., Epstein,
O.I. (2014). Release-active dilutions of diclofenac enhance anti-inflammatory effect
of diclofenac in carrageenan-induced rat paw edema model. Inflammation, 37(1), 1-9.
https://www.ncbi.nlm.nih.gov/pubmed/24005897
http://link.springer.com/article/10.1007%2Fs10753-013-9705-0